By Fabian Amman, Stephan H. Bernhart (auth.), João C. Setubal, Nalvo F. Almeida (eds.)

ISBN-10: 3319026232

ISBN-13: 9783319026237

This booklet constitutes the refereed court cases of the eighth Brazilian Symposium on Bioinformatics, BSB 2013, held in Recife, Brazil, in November 2013. The 18 normal papers awarded have been rigorously reviewed and chosen for inclusion during this booklet. The papers conceal all facets of bioinformatics and computational biology.

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Extra resources for Advances in Bioinformatics and Computational Biology: 8th Brazilian Symposium on Bioinformatics, BSB 2013, Recife, Brazil, November 3-7, 2013, Proceedings

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Since no ambiguity has been resolved in T yet, nodes T(1,1)(1) and T(1,2)(0) are created to explain genotypes (1,2) and (1,2,3,4,5), respectively. Since in column 2, genotypes 1 and 2 have symbol 2, and sites of that type have been previously resolved for those genotype, their Ids are kept to be processed after all sites on the second column that do not present ambiguity or that have all previous sites without ambiguity are resolved. Hence, genotypes 3, 4, and 5 are resolved, by creating nodes T(2,1)(1) and T(2,2)(0) .

Braga and J. Stoye Computing the Distance Given two linear genomes A and B without duplicated markers, let S1 be an optimal DCJ-indel scenario transforming A into B and let nDCJ , nins and ndel be the number of DCJ operations, insertions and deletions in S1 , such that we have dDCJ-id (A, B) = ||S1 || = nDCJ + w(nins + ndel ). As shown in [16], the scenario S1 can be transformed into another optimal scenario S2 of the same cost, so that S2 starts with nins insertions, followed by nDCJ DCJ operations, followed by ndel deletions.

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